Slice et al., Biochem Biophys Res Commun 2000
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A CRE/ATF element located at -56 was critical for Ras- and Rac induced transactivation of the COX-2 promoter, but was not required for transactivation by Rho
Hahn et al., Biochem J 2002
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Role of Rac and Cdc42 in lysophosphatidic acid mediated cyclo-oxygenase-2 gene expression ... By exclusion of RhoA and non-specific cytoskeletal effects, the results in the present study indicate an important role for Rac and/or Cdc42 in pertussis toxin-sensitive LPA mediated Cox-2 induction