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IL15 — IRAK1

Text-mined interactions from Literome

Jensen et al., J Biol Chem 2001 (Carcinoma, Hepatocellular...) : IRAK1b , a novel alternative splice variant of interleukin-1 receptor associated kinase ( IRAK ), mediates interleukin-1 signaling and has prolonged stability
Kim et al., J Biol Chem 2005 (Inflammation) : Importantly, endogenous mPLK/IRAK was activated in response to TNF-alpha or interleukin 1 treatment of primary adipose cells
Ahmad et al., Blood 2008 : Altogether, these results unequivocally show that HSV-1 induces TLR2 dependent activation of IL-15 gene expression, which requires the recruitment of both MyD88 and TIRAP/Mal and the activation of IRAK1 and TRAF6 leading to NF-kappaB translocation to the nucleus