Gene interactions and pathways from curated databases and text-mining

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LANCL1 — TLR2

Text-mined interactions from Literome

Akamine et al., Infect Immun 2005 : Treatment of L. pneumophila sonicated lysate with proteinase K and heating did not abolish TLR2 dependent IL-12p40 production
Chandra et al., Clin Exp Immunol 2008 (Leishmaniasis, Visceral...) : In addition parasite structural integrity but not viability was required for suppression of TLR2 stimulated IL-12p40 and activation of IL-10
Matsushita et al., Nature 2009 (Anemia...) : Macrophages from Zc3h12a ( -/- ) mice showed highly increased production of interleukin (IL)-6 and IL-12p40 ( also known as IL12b ), but not TNF, in response to TLR ligands
McBerry et al., J Immunol 2012 (Disease Models, Animal...) : p38 MAPK activation and IL-12p70 production was more robust from TFF2 ( -/- ) CD8+ DC compared with WT CD8+ DC and treatment of WT DC with rTFF2 suppressed TLR induced IL-12/23p40 production