Kato et al., J Immunol 2006
:
Induction of BAFF by dsRNA was dependent upon protein synthesis and IFN-alphabeta receptor-JAK-STAT signaling, as indicated by studies with cycloheximide, the JAK inhibitor I, and small interfering RNA against STAT1 and IFN-alphabeta receptor 2
Kim et al., J Leukoc Biol 2008
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Neither Stat1alpha ( a well-known transducing molecule of IFN-gamma ) nor AG490 ( a JAK inhibitor ) affected BAFF expression in response to IFN-gamma
Woo et al., J Leukoc Biol 2013
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JAK I inhibitor suppressed IFN-? induced BAFF expression
Do et al., J Immunol 2013
:
In terms of signaling intervention, ribosomal insult attenuated IFN-? activated JAK/STAT signal transduction and subsequent BAFF induction in gut epithelial cells