Shpakov et al., Bull Exp Biol Med 2004
:
A selective inhibitor of phosphatidylinositol-3-kinase wortmannin blocked the stimulatory effect of relaxin on adenylate cyclase in rat skeletal muscles and Anodonta cygnea smooth muscles ... Antibodies against protein kinase C zeta abolished the relaxin induced stimulation of adenylate cyclase in rat muscles, but not in mollusk muscles
Shpakov et al., Bull Exp Biol Med 2006
(Diabetes Mellitus, Experimental) :
In the myocardium of diabetic rats, the stimulatory effects of isoproterenol and relaxin on adenylate cyclase realized via stimulatory G-proteins were decreased to a lesser extent
Heng et al., Mol Hum Reprod 2008
:
We investigated whether relaxin can activate adenylate cyclase in primary human myometrial cells from non-pregnant tissue, and we show that relaxin is able to stimulate the generation of cAMP in a manner, which is dependent upon a tyrosine phosphorylation activity, as in the endometrium