Gene interactions and pathways from curated databases and text-mining

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CDH1 — SPARC

Text-mined interactions from Literome

Robert et al., Cancer Res 2006 (Cell Transformation, Neoplastic...) : SPARC represses E-cadherin and induces mesenchymal transition during melanoma development
Girotti et al., J Invest Dermatol 2011 (Melanoma...) : In addition, induction of the E-cadherin to N-cadherin switch by SPARC enabled melanoma cells to transmigrate across an endothelial layer through a mechanism independent to that of enhancing invasion
Fenouille et al., PloS one 2012 (Cell Transformation, Neoplastic...) : SLUG increase occurred concomitantly with SPARC mediated downregulation of E-cadherin and P-cadherin , and induction of mesenchymal traits in human melanocytes and melanoma cells ... SLUG increase occurred concomitantly with SPARC mediated downregulation of E-cadherin and P-cadherin, and induction of mesenchymal traits in human melanocytes and melanoma cells