Gene interactions and pathways from curated databases and text-mining

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IGF2 — MSTN

Text-mined interactions from Literome

Kamanga-Sollo et al., J Cell Physiol 2003 : Role of insulin-like growth factor binding protein ( IGFBP)-3 in TGF-beta- and GDF-8 ( myostatin ) -induced suppression of proliferation in porcine embryonic myogenic cell cultures
Solomon et al., Br J Hosp Med (Lond) 2006 (Muscular Atrophy) : The potential therapeutic role of the growth hormone/insulin-like growth factor axis, androgen modulators and myostatin inhibition are discussed
Miyake et al., Anim Sci J 2010 : The present study was conducted to examine whether MSTN affects IGF expression during early myogenesis in cattle ... The findings indicate that MSTN may negatively regulate myoblast differentiation by suppressing IGF-2 expression via ALK-Smad signaling