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AGTR1 — SERPINE1

Text-mined interactions from Literome

Chen et al., Arterioscler Thromb Vasc Biol 2000 : Role of the angiotensin AT(1) receptor in rat aortic and cardiac PAI-1 gene expression ... These results demonstrate a role for the AT(1) receptor in mediating the effects of Ang II on aortic and cardiac PAI-1 gene expression
Pérez-Ruiz et al., Clin Appl Thromb Hemost 2002 : Bemiparin at 1 U/mL resulted in a decreased messenger RNA ( mRNA ) PAI-1 expression, which remained unaltered when UFH had been added
Mehta et al., J Cardiovasc Pharmacol 2002 : These observations indicate that AT1 receptor activation plays an important role in the stimulation of PAI-1 expression and release in response to angiotensin II
Xia et al., J Soc Gynecol Investig 2003 (Pre-Eclampsia) : Losartan and cyclosporin A were used to determine whether the AT1-AA induced stimulation of PAI-1 secretion is through the AT1 receptor and the calcineurin-nuclear factor of activated t-cells ( NFAT ) -dependent pathway
Koh et al., Atherosclerosis 2004 (Hypertension) : Angiotensin II stimulates the expression of tissue factor ( TF ) and plasminogen activator inhibitor type-1 ( PAI-1 ), and AT1 receptor blockade (ARB) reduces PAI-1 and TF activities in experimental studies