Gene interactions and pathways from curated databases and text-mining

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PC — RELA

Text-mined interactions from Literome

Slim et al., Toxicological sciences : an official journal of the Society of Toxicology 1999 : Furthermore, PCB mediated induction of NF-kappaB and production of IL-6 were only partially blocked by alpha-NF
Kwon et al., Biol Pharm Bull 2002 (Inflammation) : However, pre treating them with a NF-kappaB pathway inhibitor, pyrrolidine dithiocarbamate, suppressed PCB induced NF-kappaB activation
Lu et al., Toxicological sciences : an official journal of the Society of Toxicology 2004 (Body Weight) : Hepatic NF-kappaB DNA binding activity and cell proliferation were increased by PCB-153 in wild-type mice but not in p50-/- mice
Glauert et al., J Nutr 2005 (Liver Neoplasms) : PCB-77 , but not PCB-153, increased hepatic NF-kappaB activity
Lim et al., Am J Physiol Heart Circ Physiol 2007 (Atherosclerosis) : A subsequent PCB induced increase in NF-kappaB DNA binding may have implications in oxidative stress mediated inflammatory mechanisms
Wang et al., Chem Biol Interact 2008 (Inflammation) : PCB77 induced oxidative stress and activation of the oxidative stress sensitive transcription factor nuclear factor kappaB (NF-kappaB) were markedly increased in the presence of LA and diminished by increasing the relative amount of ALA to LA