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FAS — IL2

Text-mined interactions from Literome

Kauma et al., J Clin Endocrinol Metab 1999 : When isolated peripheral blood lymphocytes were induced to express Fas with phytohemagglutinin ( PHA ) and interleukin-2 (IL-2) and then cocultured with trophoblast, 30 % of the lymphocytes underwent apoptosis, as determined by the in situ death ( TUNEL ) assay
Blüher et al., Eur J Endocrinol 1999 (Thyroiditis, Autoimmune) : However, in contrast to results of recent in vitro studies, in the BB/W rat Fas/FasL expression is not regulated by IL-2 , -4, -6, -10, -12, interferon gamma, and tumor necrosis factor alpha
Demir et al., Anticancer Res 1999 (Bone Neoplasms...) : We designed a prospective pilot study to evaluate in vivo effects of low dose IL-2 and IFN-alpha combination on expression of Bcl-2, FAS ( Apo-1/CD 95 ), Fas Ligand, IL-2 receptor ( CD25 ), and HLA-DR on peripheral lymphocytes in patients with advanced renal cell carcinoma
Bosanquet et al., Anticancer Res 1999 (Leukemia, Lymphocytic, Chronic, B-Cell...) : In live cells from 2 CLL specimens, IL-2 caused up-regulation of CD95 and was associated with ex vivo drug resistance
Matsumura et al., Clin Exp Rheumatol 2000 (Lymphadenitis...) : In contrast, IL-1 beta, IL-2 , IL-4, and GM-CSF had no effect on Fas levels
Gumperz et al., J Exp Med 2002 : In contrast, CD4 ( + ) CD1d restricted NKT cells potently produced both Th1 and Th2 cytokines, up-regulated perforin in response to stimulation by phorbol myristate acetate and ionomycin but not IL-2 or IL-12, and could be induced to express CD95L
Sindhi et al., J Immunol Methods 2003 : PD analyses suggested that in NHS samples containing CsA+SRL ( n=5 ), ( 1 ) PMA-Ionomycin stimulated T-cell expression of intracellular IL-2 , TNF-alpha, and IFN-gamma was inhibited by CsA, and minimally by SRL, and ( 2 ) the two agents inhibited pokeweed mitogen ( PWM ) -stimulated B-cell expression of CD54 and CD95 , but not CD86 ( ICAM-1, Fas antigen, and B7.2 ), synergistically
Jaleco et al., J Immunol 2003 : The increased susceptibility of RTE and naive CD4 ( + ) T cells to Fas induced apoptosis correlates with a significantly higher IL-2/IL-7 induced Fas expression on these T cell subsets than on memory CD4 ( + ) T cells
Du et al., Kidney Int 2005 : Apoptosis with IFN-gamma was associated with increased surface expression of Fas, while IL-2 had no effect on Fas ... IL-2 did not induce apoptosis in Fas-deficient TECs ( M3.1-lpr ) suggesting IL-2 regulation of caspase-8 activity requires Fas
Scheller et al., J Neural Transm Suppl 2006 : Stimulation of CD95 by agonistic antibodies ( 7C11 ) resulted in expression of IL-2 in primary T cells, which was further enhanced when caspase activity was blocked by ZVAD
Chen et al., Asian J Surg 2002 (Adenocarcinoma...) : In parallel, IL-2 up-regulated Fas receptor expression on HT-29 and CaCo2 cells at both protein and mRNA levels ( P < 0.05 ), which were low before treatment, while high expression of FasR on SW480 cells remained unchanged
Yamada et al., Diabetologia 1996 (Autoimmune Diseases...) : Mouse islet cell lysis mediated by interleukin-1 induced Fas
Medvedev et al., Cytokine 1997 : Cytokines further increased the Fas expression in the CD56+CD3- NK cells, with interleukin (IL)-2 being the most potent stimulus followed by IL-12, while IL-7 had no effect ... IL-2 and IL-7 equally enhanced the Fas expression in the CD56+CD3+ population, while IL-12 had a less pronounced effect
Kawakami et al., J Lab Clin Med 1998 : About 30 % of unstimulated PBLs expressed Fas , and the expression was augmented by interleukin-1beta (IL-1beta), IL-2 , tumor necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), or PMA plus ionomycin
Ayroldi et al., Blood 1998 : The results indicated that transcription of Fas/FasL is controlled by interleukin-2 (IL-2) production and that CD2 triggering rescues a T-cell hybridoma from AICD via decreased production of IL-2