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PTGES — PTGS2
Text-mined interactions from Literome
Yucel-Lindberg et al., Inflammation 2004
:
The
COX-2 specific inhibitor, celecoxib, in contrast to the nonspecific COX inhibitor, indomethacin, markedly
reduced mPGES-1 expression induced by IL-1beta
Gómez-Hernández et al., Atherosclerosis 2006
(Carotid Artery Diseases) :
We have studied
COX-2 , mPGES-1 and PGE2 receptors ( EPs ) expression in peripheral blood mononuclear cells ( PBMC ) and atherosclerotic plaques of 29 patients with carotid stenosis as well as the
effect of different nuclear factor-kappaB (NF-kappaB) inhibitors on COX-2,
mPGES-1 and EPs expression in cultured monocytic cells ( THP-1 )
Nagataki et al., Cell Biochem Funct 2008
:
The PAR2 triggered up-regulation of
mPGES-1 was
suppressed by inhibitors of COX-1, cytosolic phospholipase A ( 2 ) ( cPLA(2) ) and MEK, but not
COX-2
Kunze et al., Prostaglandins Other Lipid Mediat 2010
(Inflammation) :
IL1beta, TNF-alpha and LPS
enhanced the expression of COX-2 and
mPGES1 whereas phorbol ester enhanced
COX-2 expression only
Ikeda-Matsuo et al., Br J Pharmacol 2010
(Brain Ischemia...) :
This study examines the hypothesis that
mPGES-1 activity is
required for
COX-2 to cause neuronal damage in ischaemic injury