Hong et al., J Neuroimmunol 1993
(Neuroblastoma) :
Intercellular adhesion molecule-1 expression induced by interleukin (IL)-1 beta or an IL-1 beta fragment is blocked by an IL-1 receptor antagonist and a soluble IL-1 receptor ... The effects of a recombinant human interleukin-1 (IL-1) receptor antagonist ( IL-1ra ) and a recombinant human soluble IL-1 receptor ( sIL-1R ) on cytokine induced intercellular adhesion molecule-1 ( ICAM-1 ) expression in a human glioblastoma cell line and a neuroblastoma cell line were determined
Wang et al., Circ Res 1998
:
Because IL-1 receptor blockade reduces the IL-1 mediated autoinduction of IL-1, reduces the expression of ICAM-1 in both the graft and remote organs, and improves graft survival, it may provide a new and effective strategy to prevent the occurrence of primary cardiac graft failure