Gene interactions and pathways from curated databases and text-mining

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MESP2 — NOTCH3

Text-mined interactions from Literome

Yasuhiko et al., Proc Natl Acad Sci U S A 2006 : Tbx6 mediated Notch signaling controls somite-specific Mesp2 expression
Yasuhiko et al., Development 2008 : In cultured cells, Tbx6 binding to the Mesp2 enhancer region is essential for the activation of Mesp2 by Notch signaling
Oginuma et al., Development 2010 : To explore the establishment of normal Mesp2 expression, we performed computer simulations, which revealed that oscillating Notch signaling induces not only the periodic activation of Mesp2 but also a rostral-caudal gradient of Mesp2 in the absence of striped Notch activity in the anterior PSM
Saga et al., Adv Exp Med Biol 2008 : Genetic evidence is provided how Mesp2 regulates Notch signaling to establish segmental identity in the anterior PSM
Harima et al., Curr Opin Genet Dev 2013 (Anoxia) : Because of different oscillatory dynamics, oscillation in Fgf signaling dissociates from oscillation in Notch signaling in S-1, a prospective somite region, where Notch signaling induces Mesp2 expression when Fgf signaling becomes off