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CREB3 — MUC5AC
Text-mined interactions from Literome
Song et al., J Biol Chem 2008
(Respiratory Tract Diseases) :
ATP induced
MUC5AC mRNA levels were
regulated by
CREB via direct interaction with c-Ets1 on the MUC5AC gene promoter ( located -938 to -930 ) ... Inhibition of either
CREB or c-Ets1
inhibited ATP induced
MUC5AC gene expression ... ATP dependent
activation of
MUC5AC gene expression via
CREB-c-Ets1 may contribute to mucous cell hypersecretion associated with common respiratory disorders
Chung et al., J Immunol 2009
:
The
regulation of PGF ( 2alpha ) -induced
MUC5AC expression by
CREB was further confirmed by cAMP response element dependent MUC5AC promoter activity and by interaction between CREB and MUC5AC promoter