Gene interactions and pathways from curated databases and text-mining

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CREB3 — MUC5AC

Text-mined interactions from Literome

Song et al., J Biol Chem 2008 (Respiratory Tract Diseases) : ATP induced MUC5AC mRNA levels were regulated by CREB via direct interaction with c-Ets1 on the MUC5AC gene promoter ( located -938 to -930 ) ... Inhibition of either CREB or c-Ets1 inhibited ATP induced MUC5AC gene expression ... ATP dependent activation of MUC5AC gene expression via CREB-c-Ets1 may contribute to mucous cell hypersecretion associated with common respiratory disorders
Chung et al., J Immunol 2009 : The regulation of PGF ( 2alpha ) -induced MUC5AC expression by CREB was further confirmed by cAMP response element dependent MUC5AC promoter activity and by interaction between CREB and MUC5AC promoter