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KRAS — PI3

Text-mined interactions from Literome

Forti et al., An Acad Bras Cienc 2006 (Adrenal Cortex Neoplasms...) : We previously reported that this genetic lesion leads to high constitutive levels of activation of the c-Ki-Ras-GTP -- > PI3K -- > Akt signaling pathway ( Forti et al. 2002 )
Levallet et al., Mol Cancer Ther 2012 (Carcinoma, Non-Small-Cell Lung...) : siRNA K-Ras knockdown, inhibition of RAF/MEK ( MAP-ERK kinase ) and phosphoinositide 3-kinase (PI3K)/AKT signaling, and hypoxia were shown to downregulate TUBB3 expression in bronchial cells