Gene interactions and pathways from curated databases and text-mining

◀ Back to NFKBIA

BIRC3 — NFKBIA

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Erl et al., Circ Res 1999 : Transfer of IkappaBalpha reduced human IAP-1 mRNA levels, which suggested that IAP-1 is transcriptionally regulated by NF-kappaB
Yanai et al., J Infect Dis 2003 (Stomach Neoplasms) : Super-repressor IkappaBalpha or NF-kappaB inhibitor reduced c-IAP2 transactivation by H. pylori, and exogenous expression of c-IAP2 inhibited apoptosis seen with H. pylori
von Wnuck Lipinski et al., Circ Res 2006 : The mechanism by which NF-kappaB was protecting SMC against collagen fragment induced apoptosis was a transcriptional activation of several endogenous caspase inhibitors of the inhibitor of apoptosis protein (IAP) family as : ( 1 ) the expression of xIAP, c-IAP2 , and survivin was potently induced by collagen fragments ; ( 2 ) IAP expression was abrogated by superrepressor IkappaBalpha ; and ( 3 ) knockdown of each of the 3 IAPs by small interfering RNA ( siRNA ) resulted in enhanced apoptosis after collagen fragment treatment