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HNRNPK — KHDRBS1

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: KHDRBS1 → HNRNPK (directlyDecreases, HNRNPK Activity) Yang et al., Oncogene 2002*
  Evidence: We demonstrated that hnRNP K significantly inhibited Sam68-mediated, but not Rev-mediated, RRE-dependent gene expression. We further showed that Sam68, but not a non-functional mutant Sam68p21, inhibited transcriptional activation of CT element by hnRNP K We propose that the direct interaction of Sam68 and hnRNP K adversely affect the activities of both proteins in signal transduction pathways of both transcriptional and post-transcriptional events.

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: HNRNPK — KHDRBS1 Yang et al., Oncogene 2002*
• IRef Bind_translation Interaction: HNRNPK — KHDRBS1 (affinity chromatography technology) Yang et al., Oncogene 2002*
• IRef Bind_translation Interaction: HNRNPK — KHDRBS1 (two hybrid) Yang et al., Oncogene 2002*
• IRef Bind_translation Interaction: HNRNPK — KHDRBS1 (coimmunoprecipitation) Yang et al., Oncogene 2002*
• IRef Biogrid Interaction: HNRNPK — KHDRBS1 (direct interaction, two hybrid) Hegele et al., Mol Cell 2012
• IRef Biogrid Interaction: HNRNPK — KHDRBS1 (physical association, affinity chromatography technology) Yang et al., Oncogene 2002*
• IRef Biogrid Interaction: HNRNPK — KHDRBS1 (direct interaction, pull down) Yang et al., Oncogene 2002*
• IRef Biogrid Interaction: HNRNPK — KHDRBS1 (direct interaction, two hybrid) Yang et al., Oncogene 2002*
• IRef Biogrid Interaction: HNRNPK — KHDRBS1 (direct interaction, two hybrid) Wang et al., Molecular systems biology 2011
• IRef Hprd Interaction: HNRNPK — KHDRBS1 (in vitro) Yang et al., Oncogene 2002*
• IRef Hprd Interaction: HNRNPK — KHDRBS1 (in vivo) Yang et al., Oncogene 2002*
• IRef Intact Interaction: HNRNPK — KHDRBS1 (physical association, two hybrid) Wang et al., Molecular systems biology 2011
• IRef Intact Interaction: HNRNPK — KHDRBS1 (physical association, two hybrid) Hegele et al., Mol Cell 2012
• IRef Intact Interaction: Complex of 81 proteins (association, tandem affinity purification) Pichlmair et al., Nature 2012
• IRef Ophid Interaction: HNRNPK — KHDRBS1 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005