Gene interactions and pathways from curated databases and text-mining

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MPST — RAF1

Text-mined interactions from Literome

O'Neill et al., Science 2004 : Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1 ... Conversely, depletion of Raf-1 from Raf-1+/+ mouse or human cells led to MST2 activation and apoptosis
O'Neill et al., Cell cycle (Georgetown, Tex.) 2005 : Raf-1 inhibits MST2 by preventing its dimerisation and recruiting a phosphatase that removes activating phosphorylations on MST2
Liu et al., PloS one 2012 : We further show that the phosphorylation of MST2 by c-Abl leads to the disruption of the interaction with Raf-1 proteins and the enhancement of homodimerization of MST2 proteins