Liu et al., Di Yi Jun Yi Da Xue Xue Bao 2002
(Cardiomyopathy, Hypertrophic...) :
[ Regulation of cyclin dependent kinase inhibitors by mitogen activated protein kinase in angiotensin II-stimulated vascular smooth muscle cell hypertrophy ] ... To investigate the role of mitogen activated protein kinase ( MAPK ) in the regulation of cyclin dependent kinase inhibitors ( CDKI ) in the process of vascular smooth muscle cell ( VSMC ) hypertrophy induced by angiotensin II stimulation
Lee et al., J Cell Biochem 2006
:
In addition, PD 98059 ( a MEK inhibitor ), SB 203580 ( a p38 MAPK inhibitor ), and SP 600125 ( a JNK inhibitor ) blocked the EGF induced stimulation of [ 3H ] -thymidine incorporation and CDK-2/4 expression
Benson et al., Blood 2009
(MAP Kinase Signaling System) :
The effect results at least in part via enhanced MAPK mediated modulation of p27 and CDK4