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HSP90AA1 — INS

Text-mined interactions from Literome

Takahashi et al., J Biol Chem 2003 : In bovine aortic endothelial cells ( BAECs ), the effects of vascular endothelial growth factor ( VEGF ) and insulin on eNOS-HSP90-Akt complex formation and eNOS activation were compared ... GA prevented insulin induced association of HSP90 , Akt and CaM with eNOS and inhibited eNOS activation in BAECs
Ranganathan et al., Trends Pharmacol Sci 2010 (Motor Neuron Disease...) : Various therapeutic approaches have shown efficacy in mouse models, including androgen reduction, heat shock protein 90 (HSP90) inhibition and insulin-like growth factor (IGF)-1 overexpression
Kuhlow et al., Aging 2010 (Glucose Intolerance) : Telomerase deficiency impairs glucose metabolism and insulin secretion
Ota et al., J Biol Chem 2012 : Cdc37/Hsp90 protein mediated regulation of IRE1a protein activity in endoplasmic reticulum stress response and insulin synthesis in INS-1 cells ... In INS-1 cells, Hsp90 inhibition and disruption of IRE1a-Cdc37 interaction both induced an ER stress response and impaired insulin synthesis and secretion