Gene interactions and pathways from curated databases and text-mining

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BRCA3 — MYC

Text-mined interactions from Literome

Li et al., J Biol Chem 2002 (Breast Neoplasms) : Although Nmi or BRCA1 alone had no effect on c-Myc induced hTERT promoter activity, BRCA1 together with Nmi significantly inhibited this c-Myc induced hTERT promoter activity ( approximately 75 % inhibition )
Katiyar et al., Mol Endocrinol 2009 : However, BRCA1 overexpression inhibited the R5020 induced recruitment of PR to the c-Myc and mouse mammary tumor virus progesterone response elements (PREs) and blocked R5020 stimulated c-Myc expression, whereas BRCA1 underexpression did the opposite