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BRCA3 — MYC
Text-mined interactions from Literome
Li et al., J Biol Chem 2002
(Breast Neoplasms) :
Although Nmi or BRCA1 alone had no effect on c-Myc induced hTERT promoter activity,
BRCA1 together with Nmi significantly
inhibited this
c-Myc induced hTERT promoter activity ( approximately 75 % inhibition )
Katiyar et al., Mol Endocrinol 2009
:
However,
BRCA1 overexpression inhibited the R5020 induced recruitment of PR to the c-Myc and mouse mammary tumor virus progesterone response elements (PREs) and
blocked R5020 stimulated
c-Myc expression, whereas BRCA1 underexpression did the opposite