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MCM7 — PPARG

Text-mined interactions from Literome

Bruemmer et al., Mol Endocrinol 2003 : Overexpression of dominant negative PPARgamma or addition of a PPARgamma antagonist, GW 9662, blocked nTZDpa inhibition of MCM7 transcription ... Adenovirus mediated overexpression of constitutively active PPARgamma inhibited MCM7 expression in a similar manner as the nTZDpa ... These findings provide strong evidence that activation of PPARgamma attenuates MCM7 transcription and support the important role of this nuclear receptor in regulating vascular smooth muscle cell proliferation
Liu et al., PPAR research 2009 : Furthermore, the ERK specific-inhibitor PD98059 blocked DN-PPARgamma induced phosphorylation of Rb and expression of cyclin A and MCM7