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LPA — SELP

Text-mined interactions from Literome

Zhao et al., Thromb Res 2000 : The present study assessed the effects of native and oxidized LDL ( n-LDL and ox-LDL ) and Lp(a) ( n-Lp(a) and ox-Lp(a) ) on the expression of P-selectin in cultured human umbilical vein endothelial cells ( HUVECs ) ... Results showed that P-selectin protein expression was not influenced by n-LDL, but was moderately increased by ox-LDL and n-Lp(a) ... These results demonstrate that ox-Lp(a) can induce P-selectin expression in HUVECs, which may thereby influence the pathogenesis of athersclerosis
Osborn et al., Am J Physiol Cell Physiol 2007 : Here we show that recombinant pGSN modestly inhibited LPA induced P-selectin upregulation by human platelets in the presence of albumin ( P < 0.0001 )