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DISC1 — EPHB2

Text-mined interactions from Literome

Shinoda et al., J Neurosci 2007 : These results suggest that DISC1 is required for NT-3 induced axon elongation and ERK activation at the distal part of axons by recruiting Grb2 to axonal tips
Park et al., J Toxicol Sci 2010 : Inhibiting ERK significantly decreased the caspase-3,-8 activity in MEK-1 inhibitor treated MRC-5 cells compared to the control.The DISC formation, initial event of extrinsic apoptotic pathway, is a primary component of CSE- induced death in MRC-5, and ERK activation plays an active role in the DISC formation and downstream pathway