Gene interactions and pathways from curated databases and text-mining

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ACR — CCND1

Text-mined interactions from Literome

Suzui et al., Cancer Res 2002 (Carcinoma, Hepatocellular...) : Cotreatment of HepG2 human hepatoma cells with the proteasome inhibitor N-acetyl-Leu-Leu-norleu-al did not prevent the ACR induced decrease in cyclin D1 protein, in contrast to the protective effect of N-acetyl-Leu-Leu-norleu-al on the cyclin D1 protein in cells treated with all-trans-retinoic acid ... Nevertheless, even in the presence of excess beta-catenin, ACR markedly inhibited the transcriptional activity of the cyclin D1 promoter
Shimizu et al., Clin Cancer Res 2004 (Carcinoma, Squamous Cell) : Reporter assays indicated that ACR inhibited the transcriptional activity of the cyclin D1 , c-fos, and activator protein promoters