Gene interactions and pathways from curated databases and text-mining

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IL1A — VIP

Text-mined interactions from Literome

Eskay et al., Endocrinology 1992 : Stimulation of VIP and substance P biosynthesis by forskolin was markedly enhanced by IL-1 alpha , while forskolin stimulation of enkephalin and neurotensin biosynthesis was unaffected
Persson et al., Biochem Biophys Res Commun 2005 : Furthermore, IL-1beta stimulated IL-6 promoter activity in the osteoblastic cell line MC3T3-E1 stably transfected with a human IL-6 promoter/luciferase construct, and both VIP , and the related neuropeptide PACAP-38, increased the effect of IL-1beta in a synergistic manner
Dallos et al., Neuropeptides 2006 (Inflammation) : The aims of this study were a systematic investigation of the effects of the neuropeptides substance P ( SP ), calcitonin gene related peptide (CGRP), vasoactive intestinal polypeptide (VIP) and galanin (GAL) on the inflammatory cytokine production ( IL-1alpha , IL-8 and TNF-alpha ) of the keratinocytes, and a study of their role in the production and secretion of nerve growth factor (NGF) and its precursor molecule ( proNGF )
Kelleher et al., J Immunol 1991 : Our results demonstrated that vasoactive intestinal peptide , the beta-adrenergic agonist, isoproterenol, PGE2, IL-1 alpha , IL-1 beta, and TNF-alpha significantly increased media SC levels in control or androgen containing cell cultures
Wang et al., Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2007 : VIP could regulate the expression pattern of IL-1 , IL-6, TGF-beta and FasL by Leydig cells, which may contribute to maintain immune privilege of the testis
Spangelo et al., Endocrinology 1991 : In the presence of VIP and PGE2, IL-1 alpha and IL-1 beta increased IL-6 release without any apparent further change in extracellular or intracellular cAMP
Brenneman et al., Int J Dev Neurosci 1995 : These data indicate that VIP produced an increase in the secretion of IL-1 alpha while depleting IL-1 alpha mRNA
Lieb et al., J Neuroimmunol 1996 : We demonstrate that the neuropeptides SP, vasoactive intestinal peptide , substance K. cholecytokinine, alpha-endorphin and beta-endorphin are consistently unable to induce the synthesis of IL-1 and IL-6 in human peripheral blood monocytes