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HMGB1 — RNF19A
Text-mined interactions from Literome
Kawahara et al., Cardiovasc Pathol 2008
(Inflammation) :
C-reactive protein
induces high-mobility group box-1 protein release through activation of
p38MAPK in macrophage RAW264.7 cells
Yuk et al., Antioxid Redox Signal 2009
(Inflammation) :
In addition,
HMGB1 induced activation of
p38 and c-Jun N-terminal kinase (JNK), but not extracellular signal regulated kinase 1/2, was strongly abrogated by the overexpression of APE1 ... In addition,
HMGB1 induced
activation of
p38 and c-Jun N-terminal kinase (JNK), but not extracellular signal regulated kinase 1/2, was strongly abrogated by the overexpression of APE1
Kawahara et al., Int J Mol Med 2008
(Atherosclerosis...) :
The
p38MAPK inhibitor SB203580 and the 5-HT1B antagonist GR55526 markedly
inhibited HMGB1 release from 5-HT stimulated HUVECs
Nadatani et al., Am J Pathol 2012
(Peptic Ulcer) :
In wild-type mice, recombinant human
HMGB1 aggravated indomethacin induced small intestinal damage ; enhanced the mRNA expression levels of tumor necrosis factor a (TNF-a), monocyte chemotactic protein 1, and KC ; activated nuclear factor kappa B ; and
stimulated phosphorylation of the mitogen activated protein kinases
p38 , extracellular signal regulated kinase ( ERK ), and c-Jun N-terminal kinase (JNK)