◀ Back to IL12A
IL12A — KLRC1
Text-mined interactions from Literome
Seo et al., Clin Exp Immunol 2000
(Epstein-Barr Virus Infections...) :
Freshly isolated leukaemic NK cells transcribed mRNA for CD94 associated molecule NKG2C at an abnormally high level, and upon
stimulation with IL-2 and/or
IL-12 they expressed
NKG2A as well
Derre et al., J Immunol 2002
(Melanoma) :
Expression of
CD94/NKG2-A on human T lymphocytes is
induced by
IL-12 : implications for adoptive immunotherapy ... Expression of
CD94/NKG2-A on human T lymphocytes is
induced by
IL-12 : implications for adoptive immunotherapy ... We show that
IL-12 induces the expression of
NKG2-A and/or CD94 by CD8 ( + ) T cells in culture, and that this induction was mediated neither by IFN-gamma nor by IL-15 ... We also show, using the redirected killing assay, that
IL-12 induced expression of both CD94 and
NKG2-A led to the acquisition by T cells of a functional inhibitory receptor
Zhang et al., Hum Immunol 2008
:
In the present study, we explored the
effect of
IL-12 upregulation on the NK receptor
NKG2D and on the promotion of NK cell function