◀ Back to AHSA1

AHSA1 — HSPB1

Text-mined interactions from Literome

Kumar et al., Proteomics 2003 (Ischemia) : While JNK activation was linked to apoptosis, activated-p38 was involved in phosphorylation of Hsp27
Mizutani et al., Biochem Biophys Res Commun 2004 (MAP Kinase Signaling System...) : The p38 MAPK inhibitor, SB203580, inhibited effectively phosphorylation of HSP-27 , CREB, and eIF4E in SARS-CoV infected cells
Dubroca et al., Hypertension 2005 : Finally, phosphorylation of p38 was blocked by Y27632 and HSP27 phosphorylation was inhibited by SB203580 and Y27632
Berkowitz et al., J Biol Chem 2005 (Pemphigus) : Inhibition of p38MAPK activity prevented PV IgG induced HSP27 phosphorylation, keratin filament retraction, and actin reorganization
Rafiee et al., Am J Physiol Cell Physiol 2006 : The p38 MAPK inhibitor ( SB-203580 ) and p38 MAPK siRNA blocked Hsp27 and Hsp70 mRNA induction, suggesting a role for MAPKs in the HEMEC heat shock response
Niswander et al., Brain Res 2006 : We conclude from these results that 14-3-3epsilon synthesis and p38 mediated HSP27 phosphorylation in the hippocampus are parallel responses to the hyperosmotic environment
Zoubeidi et al., Cancer Res 2007 (Prostatic Neoplasms) : Androgen bound AR induces rapid Hsp27 phosphorylation on Ser ( 78 ) and Ser ( 82 ) residues in an AR- and p38 kinase dependent manner
Eguchi et al., Proteomics 2008 (Anoxia) : Proteomic analysis of hypoxia induced tube breakdown of an in vitro capillary model composed of HUVECs : potential role of p38 regulated reduction of HSP27
Shin et al., J Obstet Gynaecol Res 2009 (Pre-Eclampsia) : The interaction between Hsp27 and MAPK was increased, suggesting that phosphorylation of Hsp27 might be induced by p38 and ERK in placentas from patients with pre-eclampsia
Kwon et al., J Endod 2010 : Inhibiting p38 MAPK with SB203580 blocked TGFbeta1 induced Hsp27 activation and cell migration
Kato et al., Endocrinology 2011 : On the other hand, anisomycin, a p38 MAPK activator, caused the phosphorylation of HSP27 in both sphingosine 1-phosphate stimulated untransfected MC3T3-E1 cells and HSP27 transfected MC3T3-E1 cells
Shiryaev et al., Journal of molecular signaling 2011 : Both stress and cAMP elevating stimuli can cause F-actin remodeling, but whereas the in vivo role of p38MAPK-MK2 in stress triggered HSP27 phosphorylation and actin reorganization is well established, it is not known whether MK2 is involved in cAMP/PKA induced F-actin rearrangements
Liu et al., J Cell Physiol 2012 (MAP Kinase Signaling System) : Our results suggest that LeTx might cause vascular leak through inactivating p38-MK2-HSP27 signaling and that activating HSP27 phosphorylation specifically restores p38 signaling and blocks anthrax LeTx toxicity
Li et al., J Trauma 2011 (Disease Models, Animal...) : TH increases phosphorylation of p38? during both HS and early resuscitation, but attenuates phosphorylation of p38a, increases Akt/HspB1 interaction, and modulates Akt phosphorylation during HS and resuscitation
Rousseau et al., Oncogene 1997 : Inhibition of p38 activity by the specific inhibitor SB203580 led to an inhibition of HSP27 phosphorylation, actin reorganization and cell migration