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LEP — NPPA

Text-mined interactions from Literome

Beltowski et al., Obes Res 2002 : The results indicate that leptin stimulates systemic NO production ; leptin prevents blood pressure elevation induced by acute NO blockade, suggesting that leptin also triggers additional hypotensive mechanisms ; and ANP is not involved in renal and vascular effects of leptin
Moro et al., Diabetologia 2007 (Inflammation...) : The inhibitory effects of ANP on leptin and growth related oncogene-alpha secretions were not seen under selective hormone-sensitive lipase inhibition
Yuan et al., Am J Physiol Regul Integr Comp Physiol 2010 (Hypertension) : Leptin reduces plasma ANP level via nitric oxide dependent mechanism ... N ( omega ) -nitro-l-arginine methyl ester prevented the effects of leptin on the reduction of ANP level ... These data suggest that leptin inhibits ANP secretion indirectly through nitric oxide without changing basal or isoproterenol induced ANP secretion