Gene interactions and pathways from curated databases and text-mining

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CTGF — FOS

Text-mined interactions from Literome

Yu et al., J Immunol 2009 : Thrombin induced CTGF expression and CTGF-luciferase activity were inhibited by a protease activated receptor 1 antagonist ( SCH79797 ), the dominant negative mutants (DNs) of ASK1 and JNK1/2, and an AP-1 inhibitor ( curcumin )
Tran et al., Arthritis Rheum 2010 : Further evidence of Smad3 and AP-1 involvement was seen when DN-Smad3, SiRNA-Smad3, Smad7, and DN-AP-1 suppressed TGFbeta mediated activation of the CTGF promoter
Liu et al., PloS one 2012 (MAP Kinase Signaling System) : CTGF mediated increase of NF-?B and AP-1 luciferase activity was inhibited by SB203580 and SP600125 or ASK1 shRNA or p38 and JNK mutant
Liu et al., Biochim Biophys Acta 2013 (Inflammation...) : CTGF mediated increase of NF-?B and AP-1 luciferase activity was inhibited by FAK, MEK, and ERK inhibitors or mutants