We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.
UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to NPY

NPY — PRKAG2

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Namkoong et al., Diabetes 2005 (Diabetes Mellitus, Experimental...) : Chronic insulin treatment or suppression of hypothalamic AMPK activity completely prevented diabetes induced changes in food intake as well as in hypothalamic AMPK activity and mRNA expression of neuropeptide Y and proopiomelanocortin
Ropelle et al., Diabetes 2008 (Weight Loss) : Leucine and HPD decrease AMPK and increase mTOR activity in the hypothalamus, leading to inhibition of neuropeptide Y and stimulation of pro-opiomelanocortin expression
Verhulst et al., Regul Pept 2012 (Diabetes Mellitus, Experimental) : A role for the energy sensor AMP activated protein kinase (AMPK) and its downstream effector uncoupling protein 2 (UCP2) in the stimulatory effect of exogenous ghrelin on NPY/AgRP expression and food intake has been suggested