Gene interactions and pathways from curated databases and text-mining

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PRKCB — RELA

Text-mined interactions from Literome

Saijo et al., J Exp Med 2002 : Using mice deficient for protein kinase C beta (PKCbeta) we show an essential role of PKCbeta in the phosphorylation of IKKalpha and the subsequent activation of NF-kappaB in B cells
Su et al., Nat Immunol 2002 (Lymphoma, B-Cell) : PKC-beta controls I kappa B kinase lipid raft recruitment and activation in response to BCR signaling ... Here, we demonstrate that PKC-beta is specifically required for B cell receptor (BCR) mediated NF-kappa B activation
Antony et al., Exp Cell Res 2003 (Calcium Signaling) : Pharmacological inhibition of PKC isozymes and Ras revealed that the BCR induced activation of NF-kappaB requires conventional PKCbeta , whereas that of NFAT may involve non-conventional PKCdelta and Ras pathways
Banan et al., Am J Physiol Cell Physiol 2004 : We hypothesized that EGF induced activation of PKC-beta1 prevents oxidant induced activation of NF-kappaB and the consequences of NF-kappaB activation, F-actin, and barrier dysfunction
Guo et al., Curr Opin Immunol 2004 : Recent evidence indicates that PKCbeta might regulate inhibitor of kappaB kinase (IKK) and NF-kappaB activation through interaction with the CARMA1/Bcl10/MALT signaling complex in BCR microdomains
Shah et al., Eur J Cancer Prev 2006 (Colorectal Neoplasms) : Chronic c-9,t-11-CLA and t-10, c-12-CLA treatment inhibited DCA induced PKC beta1 and PKC delta translocation and also inhibited NF-kappaB activation