Gene interactions and pathways from curated databases and text-mining

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LEP — SH2B2

Text-mined interactions from Literome

Li et al., Endocrinology 2006 (Body Weight...) : SH2-B and APS, two members of a pleckstrin homology and SH2 domain containing adaptor family, promote both insulin and leptin signaling in a similar fashion in cultured cells
Li et al., Endocrinology 2007 : In mice, SH2B1 regulates energy and glucose homeostasis by enhancing leptin and insulin sensitivity