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PCNA — RBL2

Text-mined interactions from Literome

Howard et al., Cancer Res 2000 : Here we found that induction of pRb2/p130 in vivo specifically inhibits cyclin A- and cyclin E-associated kinase activity and by doing so induces p27Kip1 levels presumably by inhibiting p27Kip1 targeted proteolysis by cyclin E-Cdk2 phosphorylation of p27Kip1
Carroll et al., J Biol Chem 2000 (Breast Neoplasms) : A pure estrogen antagonist inhibits cyclin E-Cdk2 activity in MCF-7 breast cancer cells and induces accumulation of p130-E2F4 complexes characteristic of quiescence
Harvat et al., J Invest Dermatol 2001 (Carcinoma, Squamous Cell) : The interferon-gamma induced irreversible growth arrest state is characterized by inhibition of cyclin dependent kinases, prevention of Rb and p130 ( Rb2 ) phosphorylation, and increases in p27 ( Kip1 ), p16(Ink4a), and p130 proteins, together with a transient increase in p21 ( Waf1/Cip1 )
Poplawski et al., Thyroid research 2008 : p107 and p130 inhibits activity of cyclin/cdk2 complexes