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CAPN11 — MAP2

Text-mined interactions from Literome

Hoskison et al., Exp Neurol 2006 : Microtubule disruption, not calpain dependent loss of MAP2 , contributes to enduring NMDA induced dendritic dysfunction in acute hippocampal slices ... In addition, it appears that rather than underlying the initial disruption of microtubule structure via MAP2 proteolysis, calpain activity instead may contribute to the degradation of irregularly aggregated MAP2 observed following microtubule depolymerization
Inuzuka et al., Brain Res 1990 (Ischemic Attack, Transient) : Our results suggest that calpain is partially involved in the degradation of MAP2 , and that the use of calpain inhibitors can be a useful clinical approach to cerebral ischemia
Johnson et al., J Neurochem 1991 : Among other things, these results suggest a role for the calpain induced degradation of MAP-2 , as well as spectrin, in such physiological processes as alterations in synaptic efficacy, dendritic remodeling, and in pathological processes associated with neurodegeneration
Guo et al., PloS one 2012 (Creutzfeldt-Jakob Syndrome...) : Markedly increased calpain level might contribute to the reduction of MAP2
Johnson et al., J Neurosci Res 1993 : The effects of cAMP dependent protein kinase ( cAMP-PK ) and Ca2+/calmodulin dependent protein kinase II ( CaMKII ) phosphorylation on the calpain mediated degradation of microtubule associated protein 2 (MAP-2) were studied