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IL6 — TSLP
Text-mined interactions from Literome
Wong et al., Am J Respir Cell Mol Biol 2010
(Asthma) :
TSLP could significantly delay eosinophil apoptosis, up-regulate cell surface expression of adhesion molecule CD18 and intercellular adhesion molecule-1, but down-regulate L-selectin, enhance eosinophil adhesion onto fibronectin, and
induce the release of inflammatory cytokine
IL-6 and chemokines CXCL8, CXCL1, and CCL2 ( all P < 0.05 )
Shan et al., J Immunol 2010
(Respiratory Hypersensitivity) :
Thymic stromal lymphopoietin receptor
mediated IL-6 and CC/CXC chemokines expression in human airway smooth muscle cells : role of MAPKs ( ERK1/2, p38, and JNK ) and STAT3 pathways
Xie et al., Am J Reprod Immunol 2013
(Neovascularization, Pathologic...) :
It has been showed that recombinant human TSLP ( rhTSLP ) can significantly increase Ki67 and CD62E expression in HUVECs and interleukin-6 (IL-6) levels from HeLa and CaSki cells ; on the contrary, anti-human
TSLP or TSLPR neutralizing antibody down-regulates the expression of Ki67, angiogenesis-relative molecules CD62E, and CD105 in HUVECs cocultured with HeLa or CasKi cells and
inhibits IL-6 secretion from HeLa and CaSki cells