Park et al., Breast Cancer Res Treat 2010
(Breast Neoplasms) :
Taken together, these results suggest that upregulation of DR5 by ?-T3 treatment is dependent on JNK and p38 MAPK activation which is mediated by ER-stress
Yan et al., J Cancer Res Clin Oncol 2012
(Breast Neoplasms...) :
Inhibition of the activation of ERK, JNK and p38 MAPK by specific inhibitors attenuated DR4 and DR5 up-regulation
Woo et al., Biochem Biophys Res Commun 2013
(Glioma) :
Taken together, our findings indicate that the increased expression of DR5 in a p38 MAPK dependent manner plays an important role in the sensitization of MK886 to TRAIL induced apoptosis