Gene interactions and pathways from curated databases and text-mining

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CDK2 — JUN

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Zhan et al., Arterioscler Thromb Vasc Biol 2002 : Furthermore, protein kinase assay showed that Ad-DN-c-Jun blocked PDGF-BB induced activation of cyclin dependent kinase 2
Srivastava et al., Mol Cell Biol 2012 : The CARMA1 binding site in ADAP is critical for mitogen activated protein ( MAP) kinase kinase 7 (MKK7 ) phosphorylation and recruitment to the protein kinase C ? ( PKC? ) signalosome and subsequent c-Jun kinase (JNK) mediated Cdk2 induction
Jalili et al., J Natl Cancer Inst 2012 (MAP Kinase Signaling System...) : Using a dominant negative approach, in vitro cell proliferation assays, western blots, and flow cytometry showed that MAPK signaling via BRAF ( V600E ) promotes melanoma cell proliferation at G1 through AP-1 mediated negative regulation of the INK4 family member, cyclin dependent kinase inhibitor 2C ( CDKN2C ), and the CIP/KIP family member, cyclin dependent kinase inhibitor 1A ( CDKN1A )