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CCND1 — PRKAR2A
Text-mined interactions from Literome
Lamb et al., Mol Cell Biol 2000
(Breast Neoplasms) :
Further, we show that culture of MCF-7 cells on a cellular substratum of murine preadipocytes also enhanced the functional interaction between
cyclin D1 and ER in a
PKA dependent manner
Mantovani et al., J Clin Endocrinol Metab 2005
(Adenoma...) :
Moreover, in group 2,
PKA blockade by the specific inhibitor PKI
increased cyclin D1 expression ( 96 +/- 25 % over basal ) and ERK1/2 activity ( 116 +/- 28 % over basal )
Fassett et al., Mol Biol Cell 2006
:
PKA inhibition also
restored ERK activation,
cyclin D1 expression and G1-S progression on collagen gel, but had no effect on cells adherent to collagen film
Friedrichsen et al., J Endocrinol 2006
:
We conclude that incretin induced beta-cell replication is dependent on
cAMP/PKA , p42 MAPK and PI3K activities, which may
involve transcriptional induction of
cyclin D1
Taurin et al., Am J Physiol Cell Physiol 2008
:
Using the PKA inhibitor PKI or dominant negative TCF-4 mutant, we show that ATP induced
cyclin D1 promoter activation, cyclin D1 protein expression, and proliferation of VSMC are all
dependent on
PKA and TCF activities