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IDO1 — IL4

Text-mined interactions from Literome

Chaves et al., Eur J Immunol 2001 : IL-4 and IL-13 regulate the induction of indoleamine 2,3-dioxygenase activity and the control of Toxoplasma gondii replication in human fibroblasts activated with IFN-gamma
Prandota et al., Am J Ther 2007 (Headache Disorders, Secondary...) : On the other hand, IL-4 and TGF-beta can suppress IDO activity in some cells, for example human monocytes and fibroblasts, which is consistent with metabolic pathways controlled by IDO being a significant contributor to the proinflammatory system
Yadav et al., Glia 2007 : IFN-gamma induced IDO and WRS expression in microglia is differentially regulated by IL-4 ... Interestingly, we observed that both IL-4 and IL-13 greatly enhanced IFN-gamma induced IDO expression
Musso et al., Blood 1994 : Interleukin-4 inhibits indoleamine 2,3-dioxygenase expression in human monocytes ... Interleukin-4 (IL-4) is a cytokine that modulates the functional properties of monocytes/macrophages, and we investigated the effects of IL-4 on IDO ... We showed that IL-4 inhibited the induction of IDO mRNA and IDO activity by IFN gamma in human monocytes