Gotoh et al., J Rheumatol 2004
(Arthritis, Rheumatoid...) :
CD40-CD154 interaction augments the expression of inflammatory cytokines and MMP in chondrocytes and contributes to an intrinsic process of cartilage degradation in RA
Oviedo-Orta et al., Immunology 2008
:
Finally, we investigated whether CD40-CD40 ligand (CD40L) interactions were involved in T-cell stimulated MMP secretion from macrophages
Lü et al., Zhonghua Yi Xue Za Zhi 2013
(Lung Neoplasms) :
Western blot was utilized to examine the expressions of AKT and p-AKT and enzyme linked immunosorbent assay ( ELISA ) for the CD40 mediated secretion of MMP-9 Mach et al., Am J Pathol 1999
:
Ligation of CD40 on ECs induced de novo expression of gelatinase B ( MMP-9 ), increased interstitial collagenase ( MMP-1 ) and stromelysin ( MMP-3 ), and activated gelatinase A ( MMP-2 )