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SIX3 — WNT1

Text-mined interactions from Literome

Lagutin et al., Genes Dev 2003 : These results, together with those of phenotypic rescue of headless/tcf3 zebrafish mutants by mouse Six3, demonstrate that regionalization of the vertebrate forebrain involves repression of Wnt1 expression by Six3 within the anterior neuroectoderm
Braun et al., Development 2003 : Consistent with the role of Wnts as posteriorizing agents in neural tissue, we found that Wnt signaling was sufficient to induce Irx3 and repress Six3 expression in forebrain explants
Lavado et al., Development 2008 : The homeobox gene Six3 represses Wnt1 transcription ... Analysis of Six3 ; Wnt1 double-null mice revealed that Six3 mediated repression of Wnt1 is necessary for the formation of the rostral diencephalon and that Six3 activity is required for the formation of the telencephalon