◀ Back to PDGFB

PDGFB — TNF

Text-mined interactions from Literome

Nishida et al., Kidney Int Suppl 1999 : Exposure to VLDL, IDL, LDL, or a high concentration of HDL enhanced the secretion of IL-6, PDGF-AB , and TGF-beta by mesangial cells, whereas TNF-alpha secretion was stimulated by oxidized LDL
Molander et al., Exp Cell Res 2000 : However, TNF-alpha affected neither the binding of PDGF-BB to cell surface receptors nor the total amount of PDGF beta-receptor in the cells, but decreased the PDGF induced in vitro kinase activity of the receptor
Cai et al., Am J Physiol Heart Circ Physiol 2003 (Myocardial Infarction) : Functional studies confirmed the senescent dysregulation of TNF-alpha receptor pathways, demonstrating that TNF-alpha induced PDGF-B expression in cardiac microvascular endothelial cells of 4-mo-old, but not 24-mo-old, rats
Shi et al., J Cardiovasc Pharmacol 2004 : In the present study, by using the antioxidant N-acetylcysteine (NAC), we investigated in human umbilical vein endothelial cells ( HUVECs ) the roles of oxidative stress in PDGF-B expression induced by tumor necrosis factor alpha (TNFalpha) and its underlying mechanisms ... These results suggest that oxidative stress mediates the TNFalpha induced expression of PDGF-B in HUVECs through redox-sensitive transcription factors, predominantly the SP-1 and possibly, to some extent of NF-kappaB
Tisato et al., Cytokine 2013 : By using pharmacological inhibitors, specific for the main pathways, NF-kB, ERK1/2 and p38 MAPK, activated by exposure of endothelial cells to TNF-a, we found that only NF-kB appeared to be significantly involved in mediating the PDGF-BB induction by TNF-a
Zhang et al., J Dermatol 1995 (Carcinoma, Squamous Cell) : Prostaglandin E1 slightly inhibited PDGF-AB production, transforming growth factor beta 1 promoted PDGF-AB production and interferon-gamma, interleukin-1 alpha, and tumor necrosis factor-alpha failed to exert any influence at all
Silberstein et al., J Neurochem 1996 : PDGF B-chain mRNA levels were increased by TGF-beta 1, TNF-alpha , TNF-alpha/TGF-beta, or IL-1-beta/TGF-beta 1, whereas PDGF A-chain mRNA levels were not consistently affected by cytokine treatments