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CTNNB1 — TNFSF11

Text-mined interactions from Literome

Shin et al., J Bone Miner Res 2005 : Dominant negative N-cadherin inhibits osteoclast differentiation by interfering with beta-catenin regulation of RANKL , independent of cell-cell adhesion ... Moreover, Wnt-3A, Ad DeltaN46 beta-catenin , and VP16DeltabetaXTCF-3 increased the expression of RANKL and enhanced the transcriptional activity of mouse RANKL promoter in ST2 cells ... Our data suggest that expression of dominant negative N-cadherin in ST2 cells suppressed osteoclastogenesis by interfering with beta-catenin regulation of RANKL independent of cell-cell adhesion
Spencer et al., J Cell Sci 2006 : Activation of Wnt signalling downregulated RANKL mRNA and protein expression, and overexpression of fulllength beta-catenin , but not transcriptionally inactive beta-catenin DeltaC ( 695-781 ), inhibited RANKL promoter activity