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INS — TP53

Text-mined interactions from Literome

Akca et al., Clin Chem Lab Med 2002 (Uterine Cervical Neoplasms) : Tumor necrosis factor-alpha induced accumulation of tumor suppressor protein p53 and cyclin dependent protein kinase inhibitory protein p21 is inhibited by insulin in ME-180S cells
Scrable et al., Exp Gerontol 2009 (Starvation) : Running on empty : how p53 controls INS/IGF signaling and affects life span
Ho et al., Cancer Cell 2009 (Bone Neoplasms...) : Regulation of Igfbp3 expression and insulin-like growth factor (IGF) signaling by Gli and p53 integrated their effect on apoptosis
Feng et al., Genes & cancer 2011 : Furthermore, they discuss the potential mechanisms by which p53 regulates aging and longevity, including the p53 regulation of insulin/TOR signaling, stem/progenitor cells, and reactive oxygen species