Gene interactions and pathways from curated databases and text-mining

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CD40 — CD79B

Text-mined interactions from Literome

Masilamani et al., Eur J Immunol 2003 : CD21 shedding is induced by stimulation with PMA plus Ca ( 2+ ) ionophore, or by stimulation of the BCR with anti-IgM+anti-CD40
Henry et al., J Immunol 2009 (Calcium Signaling) : These include BCR down-regulation, impaired proliferative responses to anti-CD40 , and diminished calcium mobilization upon stimulation with BCR dependent and independent stimuli
Ying et al., Immunobiology 2011 : It has been shown that CD40 stimulation can augment BCR induced B cell responses, but the molecular mechanism ( s ) by which CD40 regulates BCR signaling is poorly understood
Mullins et al., Mol Immunol 1998 : Finally, CD40 mediated signals induce resting B cells to accumulate the CKI, p21, while cycling B cells require both BCR- and CD40 mediated signals to maintain increased expression of p21