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FGF2 — NES

Text-mined interactions from Literome

Ahmad et al., Biochem Biophys Res Commun 2000 : These quiescent cells, located in the pigmented ciliary bodies, proliferate in the presence of FGF2 and express the neuroectodermal marker nestin
Peng et al., Zhongguo Dang Dai Er Ke Za Zhi 2006 (Hypoxia-Ischemia, Brain) : This study investigated the effect of exogenous bFGF on nestin expression in neonatal rats following hypoxia-ischemia ( HI ) and to explore the possible mechanism
Chen et al., Neurobiol Aging 2007 : Here we show that elevated FGF-2 enhances the division and nestin levels of cultured adult rat hippocampal progenitors but impairs neuronal lineage determination and maturation of these cells in culture
Sun et al., Zhonghua Er Ke Za Zhi 2007 (Hypoxia, Brain...) : ( 3 ) Exogenous bFGF could enhance the expression of nestin and GAP-43 in the brain of neonatal rats with HIBD, which may play an important role in restoration of neurons damaged due to hypoxia-ischemia
He et al., J Huazhong Univ Sci Technolog Med Sci 2012 : The results showed that FGF-2 increased the expression of Nestin , dramatically inhibited the expression of GFAP and Tuj1 and slightly suppressed the expression of CNPase
Aizman et al., Stem Cells Transl Med 2013 : Neutralization studies showed that MSC derived fibroblast growth factor 2 was a major and diffusible inducer of rat nestin , whereas MSC derived bone morphogenetic proteins ( BMPs ), particularly, BMP4, were astrogenesis mediators, predominantly acting in a coculture setting
Chang et al., Biochem Biophys Res Commun 2013 (Glioma) : The results showed that nestin expression was up-regulated by FGF-2 via de novo RNA and protein synthesis ... Our RT-PCR results showed that C6 glioma cells express FGFR1/3, and FGFRs is required for FGF-2 induced nestin expression ... Further signaling analysis also revealed that FGF-2 induced nestin expression is mediated through FGFR-MAPK-ERK signaling axis and the transcriptional factor Sp1