UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

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CPSF1 — PAPOLA

Pathways - manually collected, often from reviews:

BioCarta polyadenylation of mrna: CPSF/PAP/polyadenylated mRNA complex (CPSF3_CPSF1_CPSF4_CPSF2-PAPOLA) → CPSF/PAP complex (CPSF3_CPSF1_CPSF4_CPSF2-PAPOLA) (modification, collaborate)
BioCarta polyadenylation of mrna: CPSF/PAP/pre-mRNA complex (CPSF3_CPSF1_CPSF4_CPSF2-PAPOLA) → CPSF/PAP complex (CPSF3_CPSF1_CPSF4_CPSF2-PAPOLA) (modification, collaborate)
BioCarta polyadenylation of mrna: CPSF/PAP/pre-mRNA complex (CPSF3_CPSF1_CPSF4_CPSF2-PAPOLA) → CSTF complex (CSTF1-CSTF2-CSTF3) (modification, collaborate)
BioCarta polyadenylation of mrna: CPSF/PAP/pre-mRNA complex (CPSF3_CPSF1_CPSF4_CPSF2-PAPOLA) → CPSF/PAP/mRNA complex (CPSF3_CPSF1_CPSF4_CPSF2-PAPOLA) (modification, collaborate)
BioCarta polyadenylation of mrna: CSTF complex (CSTF1-CSTF2-CSTF3) → CPSF/PAP/mRNA complex (CPSF3_CPSF1_CPSF4_CPSF2-PAPOLA) (modification, activates)
BioCarta polyadenylation of mrna: CPSF/PAP/mRNA complex (CPSF3_CPSF1_CPSF4_CPSF2-PAPOLA) → CPSF/PAP/polyadenylated mRNA complex (CPSF3_CPSF1_CPSF4_CPSF2-PAPOLA) (mRNA polyadenylation, collaborate)
BioCarta polyadenylation of mrna: CPSF/PAP/mRNA complex (CPSF3_CPSF1_CPSF4_CPSF2-PAPOLA) → None (mRNA polyadenylation, collaborate)
BioCarta polyadenylation of mrna: CPSF/PAP/mRNA complex (CPSF3_CPSF1_CPSF4_CPSF2-PAPOLA) → PAB II (PABPN1) (mRNA polyadenylation, collaborate)
BioCarta polyadenylation of mrna: CPSF/PAP/mRNA complex (CPSF3_CPSF1_CPSF4_CPSF2-PAPOLA) → None (mRNA polyadenylation, collaborate)
BioCarta polyadenylation of mrna: CPSF/PAP/polyadenylated mRNA complex (CPSF3_CPSF1_CPSF4_CPSF2-PAPOLA) → None (mRNA polyadenylation, collaborate)
BioCarta polyadenylation of mrna: CPSF/PAP/polyadenylated mRNA complex (CPSF3_CPSF1_CPSF4_CPSF2-PAPOLA) → None (mRNA polyadenylation, collaborate)
KEGG mRNA surveillance pathway: PAPOLA/PAPOLB/PAPOLG → CPSF1 (protein-compound, binding/association)
Reactome Reaction: CPSF1 → PAPOLA (indirect_complex)
Reactome Reaction: CPSF1 → PAPOLA (reaction) Zhao et al., Microbiol Mol Biol Rev 1999, Moore et al., Cell 1985

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

IRef Biogrid Interaction: CPSF1 — PAPOLA (direct interaction, pull down) Murthy et al., Genes Dev 1995
IRef Intact Interaction: Complex of PAPOLA-PABPN1-CPSF1-NPM1 (association, anti bait coimmunoprecipitation) Sagawa et al., EMBO J 2011
IRef Intact Interaction: Complex of HNRNPL-PAPOLA-CPSF3-PCBP2-CPSF1-CPSF2-SYMPK (association, anti bait coimmunoprecipitation) Ji et al., EMBO J 2011
IRef Intact Interaction: Complex of TUT1-PAPOLA-CPSF1 (association, anti bait coimmunoprecipitation) Laishram et al., EMBO J 2010
IRef Ophid Interaction: CPSF1 — PAPOLA (aggregation, interologs mapping) Brown et al., Bioinformatics 2005