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GPX2 — SFN

Text-mined interactions from Literome

Banning et al., Mol Cell Biol 2005 : In CaCo-2 cells, GI-GPx was induced by t-butyl hydroquinone ( tBHQ ) and sulforaphane (SFN) , i.e., `` antioxidants '' known to activate the `` antioxidant response element '' ( ARE ) via electrophilic thiol modification of Keap1 in the Nrf2/Keap1 system
Krehl et al., Carcinogenesis 2012 (Cell Transformation, Neoplastic...) : Since GPx2 is induced by the chemopreventive sulforaphane (SFN) via the nuclear factor E2-related factor 2 ( Nrf2)/Keap1 system, the susceptibility of GPx2-KO and wild-type ( WT ) mice to azoxymethane and dextran sulfate sodium ( AOM/DSS ) -induced colon carcinogenesis was tested under different selenium states and SFN applications ... Similarly, SFN requires selenium but not GPx2 for being protective